Back to expert viewsThis video provides an overview of the important role apolipoprotein A1, a key functional component of high-density lipoprotein, plays in cholesterol efflux and plaque stabilization.
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Following an AMI, the risk of recurrent CV events remains high, particularly during the first 90 days. Despite advances in standard of care treatment, an unmet therapeutic need persists for these patients. This engaging symposium brings together an expert faculty to explore the mechanism of cholesterol efflux and its impact on post-AMI CV events. The panel will outline the pivotal role ApoA-I, a key functional component of HDL, plays in this setting, and discuss recent developments in the high-risk post-AMI landscape.
Listen to Prof Stephen Nicholls provide his expert insights on why the HDL hypothesis is shifting from a focus on HDL levels to HDL function. He describes ApoA-I, the key functional component of HDL, and the role it plays in the mechanism of cholesterol efflux, the pivotal first step in reverse cholesterol transport
ACC, American College of Cardiology; ACS, acute coronary syndrome; AHA, American Heart Association; AMI, acute myocardial infarction; ApoA-I, apolipoprotein A-I; ASCVD, atherosclerotic cardiovascular disease; CV, cardiovascular; ESC, European Society of Cardiology; HDL, high-density lipoprotein; LDL, low-density lipoprotein
USA-GEN-0051 | March 2024