of recurrent CV events in the first year occur in the first 90 days following an AMI1,2

~50% of recurrent CV events in the first year occur in the first 90 days following an AMI1,2



Could excess cholesterol in atherosclerotic plaque be part of the problem?

As cholesterol cannot be broken down by the body, a two-way process of influx and efflux moves cholesterol into and out of arterial plaques.3

Any imbalance between influx and efflux causes plaques to gradually become engorged with excess cholesterol.4–7

As plaque burden increases, plaques may become vulnerable to rupture, which could lead to a fatal CV event, non-fatal AMI or stroke.1,4,5,7

In the high-risk 90-day period after an AMI, already compromised cholesterol efflux continues to diminish further, increasing the risk of a recurrent CV event.1, 7-11

Learn more about how cholesterol efflux can reduce the risk of recurrent CV events7,12

More on cholesterol efflux

The cholesterol story

Learn about the role of cholesterol efflux in removing excess cholesterol from lipid-laden macrophages in arterial plaque7,12

Impact of low cholesterol efflux

Understand why a continued reduction in already impaired cholesterol efflux directly after an AMI increases the risk of a recurrent CV event8–10,13–15

What happens to cholesterol efflux after an AMI?

Learn about why patients are at a disproportionately high risk in the 90-day period post AMI1,15–18

Burden of recurrent CV events

Find out about the significant healthcare costs associated with recurrent CV events post AMI19–22

Current standard of care post AMI

Current standard of care and newer therapies have lowered the  long-term risk of recurrent CV events; however, data show that  patients are still at risk during the 90-day high-risk period after  an AMI23-30

Expert views

These resources are for global healthcare professionals to learn more about the role of cholesterol efflux and educate their patients after an AMI

Access more here right

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Sign up to receive news alerts and information about educational resources to help your patients through the 90-day high-risk period post AMI

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AMI, acute myocardial infarction; CV, cardiovascular


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30. Nair R et al. J Am Heart Assoc 2021; 10:e019270.

USA-GEN-0051 | August 2023